Health Indicators Monitoring During Treatment with Milteforan in Dog Positive for Leishmania
Abstract
Leishmaniasis is a complex disease caused by parasitic protozoans which are transmitted to a susceptible host by phlebotomine sand flies. Leishmania parasites cause leishmaniasis, with diverse epidemiological and clinical patterns. Owned dogs appeared to be a permanent, all seasons, source of infestation. Depending on the conditions of the area, some areas such as Kruja (Albania) have ideal conditions for the presence of the vector and looked to be at a higher risk of exposure to phlebotomes. The relatively high number of owned dogs found positive for leishmaniasis, indicated that leishmaniasis should be taken seriously into consideration as a disease of zoonotic importance. Dog owners were usually willing to accept euthanasia as the first choice for their dogs. For the treatment of positive cases it were used melgumine antimoniate (glucantime), 100 mg/b.w., every day, s/c, for 20-30 days in a row and allopurinol 15 -20 mg/kg b.w., per os, twice daily for 30 days. Sometimes two drugs used usually combined together. In the case of treatment and recurrence are already cost and serious injuries to bring these preparations or their combined use in the liver and kidney. On the other hand, the study shows that Milteforan can be used with high efficiency against leishmaniasis at the dogs. Monitoring of haematological and biochemical indicators showed that the dog did not even care about the liver and kidneys.
Keywords: Leishmaniasis, Milteforan, treatment, indicators, dog.
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