COMPARISON OF NONSTEROIDAL ANTI-INFLAMMATORY OF COX-1 AND COX-2 REGARDING SIDE EFFECTS IN THE ASTROINTESTINAL TRACT

Authors

  • Viola Cala PhD student, Faculty of Medical Technical Sciences University of Medicine Tirana
  • Floreta Kurti Service of Gastrohepatolology, UHC “NënëTereza” Tirana
  • Elizana Petrela Service of Statistics, UHC “NënëTereza” Tirana
  • Elona Mollsi Faculty of Medical Technical Sciences University “Aleksander Xhuvani”, Elbasan

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat symptoms caused by rheumatoid arthritis due to their ability to inhibit prostaglandin synthesis by inhibiting cyclooxygenase (COX). The side effects of NSAIDs are also associated with inhibiting prostaglandin production. Consequently, their application is problematic. NSAID selective COX-2 inhibitors give minor gastrointestinal complications. Our study aims to compare nonsteroidal anti-inflammatory inhibitors of COX-1 and COX-2 regarding side effects in the gastrointestinal tract of patients with rheumatoid arthritis.

Keywords:  Nonsteroidal anti-infammatory drugs, rheumatoid arthtritis, COX-2, gastrointestinal tract, PPIs.

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Published

2021-06-10

How to Cite

Cala, V., Kurti, F., Petrela, E., & Mollsi, E. (2021). COMPARISON OF NONSTEROIDAL ANTI-INFLAMMATORY OF COX-1 AND COX-2 REGARDING SIDE EFFECTS IN THE ASTROINTESTINAL TRACT. ANGLISTICUM. Journal of the Association-Institute for English Language and American Studies, 10(5), pp.58–63. Retrieved from https://anglisticum.org.mk/index.php/IJLLIS/article/view/2203

Issue

Vol. 10 No. 5 (2021): Volume 10, issue 5, May 2021

Section

Volume 10, No.5, May 2021

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