Gastric Cancer Associated with Helicobacter Pylori

Authors

  • Florenc Piligriu

Abstract

In spite of a decline in incidence and mortality of gastric cancer over the last decades, it is still the fourth most common cancer and the second most common cause of cancer death in the world. The differences in prevalence of gastric cancer have been explained as a multifactorial process with an interaction involving both infection with Helicobacter pylori as a triggering factor and host genetic susceptibility as an important explanation for interindividual variation in gastric cancer risk. At present, there is no definitive host genetic risk marker, and evidence suggests that each proposed host risk factor should be evaluated in specific ethnic populations to define its importance. In this review, we discuss the most relevant up to date data on genetic polymorphisms that have been associated with an increased risk for the development of gastric cancer, its potential role in the development of this neoplasia, and its interplay with the virulence factors of the bacteria.

Downloads

Published

2015-12-29

How to Cite

Piligriu, F. (2015). Gastric Cancer Associated with Helicobacter Pylori. ANGLISTICUM. Journal of the Association-Institute for English Language and American Studies, 2(1), 124–132. Retrieved from https://anglisticum.org.mk/index.php/IJLLIS/article/view/411

Issue

Vol. 2 No. 1 (2013): Volume 2, No.1, February, 2013

Section

Volume 2, No.1, February, 2013

License

Declaration/Copyright transfer:

1. In consideration of the undertaking set out in paragraph 2, and upon acceptance by ANGLISTICUM for publication of the manuscript in the Journal, I/We hereby assign and transfer publication rights to ANGLISTICUM, whereas I/We retain the copyright for the manuscript. This assignment provides ANGLISTICUM the sole right and responsibility to publish the manuscript in its printed and online version, and/or in other media formats.

2. In consideration of this assignment, ANGLISTICUM hereby undertakes to prepare and publish the manuscript in the Journal, subject only to its right to refuse publication if there is a breach of the Author’s warranty in paragraph 4 or if there are other reasonable grounds.

3. Editors and the editorial board of ANGLISTICUM are empowered to make such editorial changes as may be necessary to make the Manuscript suitable for publication.

4. I/We hereby acknowledge that: (a) The manuscript submitted is an original work and that I/We participated in the work substantively and thus I/We hereby are prepared to take public responsibility for the work; (b) I/We hereby have seen and approved the manuscript as submitted and that the manuscript has not either been published, submitted or considered for publication elsewhere; (c) The text, illustration, and any other materials included in the manuscript do not infringe upon any existing copyright or other rights of anyone.

5. I/We hereby indemnify ANGLISTICUM and the respective Editors of the Journal as mentioned in paragraph 3, and hold them harmless from any loss, expense or damage occasioned by a claim or suit by a third party for copyright infringement, or any suit arising out of any breach of the foregoing warranties as a result of publication of the manuscript.